Endocrine Abstracts

Introduction: Resistance to thyroid hormone (RTH), a syndrome reduced end-organ responsiveness to thyroid hormone.Case report: A 42 year old woman underwent near total thyroidectomy due to her enlarged thyroid with multiple nodules. At that time she had sligthly elevated values of plasma FT4, FT3 and normal TSH values and had no sign and symptoms of thyrotoxicosis or hypothyroidism. After thyroidectomy she recieved L-T4 treatment but her TSH levels remai...

Background: Congenital adrenal hyperplasia (CAH) resulting from 17 α hyroxylase enzyme deficiency (17OHD) is a rare autosomal recessive disorder. More than 150 cases were reported in the literature. Patients with 17OHD were reported to have hypoaldosteronism.Case: A 16-year-old female referred to endocrinology outpatient clinic from family medicine department with the absence of a secondary sexual characteristics and primary amenorrhea. On physical ...

Objectives: T helper1 (Th1) cells were determined to have important roles in the development of type 2 diabetes (T2D). We aimed to investigate relationship between Th1 cytokines (IFN γ, IL-2 and TNF-α) and T2D.Material and methods: The study included 32 newly diagnosed type 2 diabetic patients (T2DPs) who had not begun to take antidiabetic agents except from insulin and 30 healthy subjects (CG) who did not have glucose intoerance (fasting or af...

Introduction: Congenital adrenal hyperplasia (CAH) is a group of autosomal recessively inherited disorders that are characterised by inactivating mutations at various steps of adrenal steroidogenic pathways causing defective cortisol biosynthesis. 21-Hydroxylase enzyme deficiency (21-OHd) constitutes more than 95% of all CAH cases.Material & Methods: Medical records of patients with all forms of CAH from 19 adult endocrinology clinics located at six ...